Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

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If you are taking any other type of blood pressure medication, including products containing caffeine, you should include it in your treatment guidelines based on your blood pressure needs:

• Potential interactions with certain medications (Ex. non-steroidal anti-inflammatory drugs, phenytoin, or ketoconazole)
  • Signs of a severe heart attack or stroke (Ex. chest pain or pressure, nausea, headache, or dizziness, chest pain with or without fainting, sudden, severe headache, sweating)
  • Signs of a heart attack or stroke (Ex. shortness of breath, headache, nausea)
  • Signs of an heart failure (e.g., swelling of the hands, ankles, or feet, sudden, severe, persistent, allergic-type reactions, such as rash, itching, or swelling of the mouth and/or throat)
• Potential interactions with some medications (e.g.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

• Headache
• Indigestion
• Heartburn
• Upset stomach
• Gas
• Nausea
• Flushing

More severe side effects include:

• Painful erections or erections that last longer than 4 hours
• Sudden loss of vision
• Sudden loss of hearing
• Ringing in the ears
• Chest pain
• Shortness of breath
• Painful urination
• Increased urination frequency
• Fainting
• Dizziness
• Skin rash
• Hives
• Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read More This Side effect is also reported in a small number of cases of cryptococcal meningitis that can affect the part of your body responsible for symptoms. According to the manufacturer, Cialis can cause some side effects in some cases. Read Moreoxic symptoms of cryptococcal meningitis were reported after taking Cialis and prior to taking Cialis. Read More Or if you experience any of these side effects, seek medical attention immediately. These side effects are also reported in a small number of cases of cryptococcal meningitis that can affect the part of your body responsible for symptoms. alleged side effects of Cialis (Cialis) (rest - tadalafil) Cialis (tadalafil) Cialis (tadalafil) FAQs Cialis (tadalafil)ug of Again Cialis (tadalafil) is available as a generic medication in the U. S. There is no known connection between Cialis and urinary tract infections. Cialis (tadalafil) can cause some side effects in some cases. Read More Or if you experience chest pain during sex Cialis (tadalafil) can cause other side effects such as headache, flushing, nasal congestion, indigestion, and muscle pain. Read More Or if you experience any of these, contact your health care provider immediately.What is the covered drug? Cialis (tadalafil) is a prescription medication that is covered by most insurance plans. However, the manufacturer says that most plans pay a coverage price for Cialis. plan members can use this to access the drug. Cialis (tadalafil) is not available in the U. as of October 11, 2023. Cialis (tadalafil) is also not covered under the Health Insurance Portability and Accountabilityal Center (HIPAC) Act, which allows the U. toRarely, Cialis could cause a rare condition called tinnitus.What is the covered medication? The covered medication is a prescription medication that is covered by most plans. Although the drug is covered under most plans, the manufacturer says that most plans pay a coverage price for Cialis.

For the first time, CVS will offer a $25 coupon for its Cialis brand. For those who prefer to shop directly from CVS stores or Walmart, they may be able to save $10 off their first order from participating pharmacies.

In addition, CVS is offering a $30 coupon for its popular Cialis Cialis 20mg pill. For those who are not able to afford their Cialis brand, you can still save $15 off their first order.

As a result of these savings, CVS offers a $25 CVS discount card for its popular Cialis brand and a $30 discount card for its popular Cialis brand.

In addition, CVS is offering a $30 CVS coupon for its popular Cialis brand and a $30 coupon for its popular Cialis brand.

CVS will continue to offer the Cialis brand for a limited time and to eligible customers, you can still order the Cialis brand from CVS or Walmart. The Cialis brand is available for purchase at CVS stores and Walmart pharmacies.

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References

Erectile Dysfunction Drugs.. Updated May- April, 2019. Accessed December 16, 2019.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

• Headache
• Indigestion
• Heartburn
• Upset stomach
• Gas
• Nausea
• Flushing

More severe side effects include:

• Painful erections or erections that last longer than 4 hours
• Sudden loss of vision
• Sudden loss of hearing
• Ringing in the ears
• Chest pain
• Shortness of breath
• Painful urination
• Increased urination frequency
• Fainting
• Dizziness
• Skin rash
• Hives
• Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Show More Degeneration Changes Cialis has been shown to cause some side effects. These effects may improve with time. However, the most common side effects are not permanent and may improve with time.Degeneration Untolder Side Effects Cialis can cause very rare side effects. These may include but are not limited to:

• Stomach pain
• Gastrointestinal pain
• Dizziness when on sexual site

If you experience any such side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate intervention.

As with all prescription medications, inform your doctor if you experience any unusual abdominal pain, tenderness, or swelling. This may be a sign of fluid retention.

If you experience any unusual abdominal pain, you should contact your health care provider immediately. This is a condition where you experience fluid retention while having sex, especially when you are on Cialis. This may get worse with time.

If you experience any such unusual abdominal pain, you should contact your health care provider over an appointment. This is a condition where you experience abdominal pain when you have sex, especially when you are on Cialis.

If you experience any such changes in your heart, including a slow heart rate, sudden decrease in hearing, or prolonged slow heartbeat, you should contact your health care provider immediately. This is a very rare side effect of Cialis.

If you experience a sudden decrease in hearing or prolonged slow heartbeat, you should contact your health care provider immediately.

If you experience sudden loss of vision, you should contact your health care provider immediately.

If you experience a sudden loss of black tarry stools, you should contact your health care provider.

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